Developer Noviniti has awarded Willmott Dixon a £16.8m contract that will result in an additional 500 parking spaces at the Royal Derby.
The car park will be spread over five storeys and replace a current surface level car park. Completion is expected in summer 2025.
Ahead of main works, Willmott Dixon has already put in a temporary car park near the hospital with a park-and-ride system in operation.
Willmott Dixon recently built a 654-space multi-storey car park at Dorset County Hospital. The company is also currently on site at Darlington railway station building a 600-space multi-storey car park.